Natural (or unnatural) disasters can have an effect on the release of any media, and that’s no different for video games. Metal Gear Solid 2 was set in New York City, and after the 9/11 terrorist attacks some parts of the ending were changed because of the events.

MotorStorm: Apocalypse is a racing game that takes place in an urban setting during a natural disaster. Because of the deadly earthquakes that have hit the Christchurch region of New Zealand, Sony is reportedly not releasing the game there when it launches March 2011, though they may eventually bring it to the island nation.

Source: Kotaku