A casting call by Take-Two has provided a hint that Grand Theft Auto V is indeed in development. The recent casting call by the publisher mentioned a character James Pedeaston, “a man-boy love activist” who appeared on radio channel WCTR in Grand Theft Auto IV.
Recent rumors citing another casting list for a variety of colorful characters placed the new game in Los Angeles (or the Grand Theft Auto equivalent Los Santos, located in the state of San Andreas). Also, several URLs like CashForDeadDreams.com, StopPayingYourMortgage.net and LifeInvader.com were registered by Take-Two recently, which fits with the GTA series references to parody websites that can be loaded up on the Internet outside of the game.
Source: Ripten
